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Protein Biochemistry
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Sodium Oxamate
Sodium Oxamate from Cayman Chemical
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Citations:
(3)
Supplier Page
Supplier Page from
Cayman Chemical for
Sodium Oxamate
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Description
A derivative of pyruvate that inhibits the conversion of pyruvate to lactate via lactate dehydrogenase, thus disrupting glycolysis; studied as an inhibitor of glycolysis in various tumors
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Sodium Oxamate
Company
Cayman Chemical
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
19057
Format
A crystalline solid
Research Area
Cancer, Carbohydrate Metabolism, Endocrinology & Metabolism, Metabolism
Molecular Weight
111
Quantity
25 g
Purity
≥95%
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (3)
(1)
Functional-metabolic coupling in distinct renal cell types coordinates organ-wide physiology and delays premature ageing
Nat Commun
December 18, 2023
Jack Holcombe, Helen Weavers
inhibitors
: 2-DG (
2-deoxy-d-glucose
, 50 mM,
Sigma
, D8375),
Sodium Oxamate
(
Cayman Chemical
, 50 mM,
19057
) and
Rotenone
(
Sigma
, 5 μM, R8875) (in Schneiders medium) for 30 min at room temperature. For imaging
(2)
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer
Cell metabolism
March 7, 2023
Weiss-Sadan T, Ge M, Hayashi M, Gohar M, Yao CH, de Groot A, Harry S, Carlin A, Fischer H, Shi L,
et al
.
25867
2-Deoxyglucose,Sigma-Aldrich,Cat#: D8375
β-Nicotinamide mononucleotide
,
MedChemExpress
,Cat#:
HY-F0004
Sodium oxamate
,
Cayman
,Cat#:
19057
AZD7545,
Cayman
,Cat#:
19282
Phenylacetaldehyde,Sigma,Cat#: 107395 4-Hydroxyphenylacetaldehyde,This
(3)
Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection
Nature microbiology
October 1, 2020
Heim CE, Bosch ME, Yamada KJ, Aldrich AL, Chaudhari SS, Klinkebiel D, Gries CM, Alqarzaee AA, Li Y, Thomas VC,
et al
.
infection
. To
inhibit
host LDH,
mice
received daily i.p.
injections
of sodium oxamate (500 mg/kg; Cat. #
19057
;
Cayman Chemical
) dissolved in 0.5% Hydroxypropyl Methylcellulose beginning one day prior to
infection
. Quantification
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Sodium Oxamate from Cayman Chemical
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